Syria is the strategic depth of the Islamic Republic in the West Asian region and the link between the Islamic Republic of Iran and the Islamic Resistance in Lebanon and Palestine. The shift in the balance of power in West Asia, marked by the victory of the Islamic Revolution in Iran, the fall of Saddam Hussein in 2003, the rise of Shiites in Iraq and Lebanon, and the victory of Hezbollah in the 33-day war, persuaded regional and international rival blocs with semi-hard and soft tactics, curb the growing power of the Islamic Republic of Iran in the region. Since Syria is the link between the East-West corridor of the resistance and played an important role in Hezbollah’s victory in the 33-day war, changing the Syrian political system is on the agenda of the regional and international bloc opposing the resistance and supporters of the Zionist regime. The devastating crisis in Syria is going on with the Syrian and non-Syrian opposition acting and leading and supporting foreign networks. The Syrian opposition must be accepted as a reality in the current situation and future scenarios in Syria, which cannot be eliminated, and due to its bloody confrontation with the Syrian regime, it can be predicted they will maintain their radical action and some red lines in the future. Therefore, it is important to examine the situation of the opposition in the future-oriented scenarios of Syria by recognizing the goals, nature, method of action, political authority and foreign supporters.